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Article

Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies.

Experimental gerontology - 1 Dec 2000

Bertram L, Blacker D, Crystal A, Mullin K, Keeney D, Jones J, Basu S, Yhu S, Guénette S, McInnis M, Go R, Tanzi R

Abstract excerpt

Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder. To date, a large number of candidate genes have been associated with the disease, however none of these findings has been consistently replicated in independent datasets. In this study we report the results of family-based analyses for polymorphisms of five such candidates on chromosomes 2 (interleukin-1beta, IL-1B), 3...

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Source

Identifiers

PMID: 11113613
DOI: 10.1016/s0531-5565(00)00193-5

Genes

APBB1
BCHE
CTSD
LRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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