Article
Overlapping functions of argonaute proteins in patterning and morphogenesis of Drosophila embryos.
PLoS genetics - 25 Aug 2006
Meyer Wibke J, Schreiber Silke, Guo Yi, Volkmann Thorsten, Welte Michael A, Müller H Arno J
Abstract excerpt
Argonaute proteins are essential components of the molecular machinery that drives RNA silencing. In Drosophila, different members of the Argonaute family of proteins have been assigned to distinct RNA silencing pathways. While Ago1 is required for microRNA function, Ago2 is a crucial component of the RNA-induced silencing complex in siRNA-triggered RNA interference. Drosophila Ago2 contains an unusual...
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