Article
Detecting the presence and absence of causal relationships between expression of yeast genes with very few samples.
Journal of computational biology : a journal of computational molecular cell biology - 1 Mar 2010
Kang Eun Yong, Ye Chun, Shpitser Ilya, Eskin Eleazar
Abstract excerpt
Inference of biological networks from high-throughput data is a central problem in bioinformatics. Particularly powerful for network reconstruction is data collected by recent studies that contain both genetic variation information and gene expression profiles from genetically distinct strains of an organism. Various statistical approaches have been applied to these data to tease out the underlying biological...
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