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Article

RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions.

BMC molecular biology - 28 Oct 2009

Ordinario Ellen C, Yabuki Munehisa, Handa Priya, Cummings W Jason, Maizels Nancy

Abstract excerpt

BACKGROUND: Gene conversion depends upon the same factors that carry out more general process of homologous recombination, including homologous gene targeting and recombinational repair. Among these are the RAD51 paralogs, conserved factors related to the key recombination factor, RAD51. In chicken and other fowl, gene conversion (templated mutation) diversifies immunoglobulin variable region sequences. This...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19863810
DOI: 10.1186/1471-2199-10-98
PMCID: PMC2774322

Genes

XRCC2
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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