Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromatin structure regulates gene conversion.

PLoS biology - 1 Oct 2007

Cummings W Jason, Yabuki Munehisa, Ordinario Ellen C, Bednarski David W, Quay Simon, Maizels Nancy

Abstract excerpt

Homology-directed repair is a powerful mechanism for maintaining and altering genomic structure. We asked how chromatin structure contributes to the use of homologous sequences as donors for repair using the chicken B cell line DT40 as a model. In DT40, immunoglobulin genes undergo regulated sequ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin
Share to Chromobox Protein Homolog 5
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Conversion

Share to Gene Rearrangement, B-Lymphocyte

Share to Genomic Instability

Share to Lactose

Share to Templates, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 17880262
DOI: 10.1371/journal.pbio.0050246
PMCID: PMC1976632

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17880262-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromatin structure regulates gene conversion.PMID 17880262Read ↗

Genetic variation stimulated by epigenetic modification.Semantic proximity Read ↗

Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation.Semantic proximity Read ↗

RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions.Semantic proximity Read ↗

Brca1 in immunoglobulin gene conversion and somatic hypermutation.Semantic proximity Read ↗

Immunoglobulin gene conversion or hypermutation: that's the question.Semantic proximity Read ↗

Positive Cofactor 4 (PC4) is critical for DNA repair pathway re-routing in DT40 cells.Semantic proximity Read ↗

Immunoglobulin gene conversion: Synthesizing antibody diversification and DNA repairSemantic proximity Read ↗

Understanding the immunoglobulin locus specificity of hypermutation.Semantic proximity Read ↗

TET3 dioxygenase modulates gene conversion at the avian immunoglobulin variable region via demethylation of non‐CpG sites in pseudogene templatesSemantic proximity Read ↗

Somatic Diversification of Rearranged Antibody Gene Segments by Intra- and Interchromosomal Templated Mutagenesis.Semantic proximity Read ↗

DNA polymerases nu and theta are required for efficient immunoglobulin V gene diversification in chicken.Semantic proximity Read ↗

Immunoglobulin enhancers increase RNA polymerase 2 stalling at somatic hypermutation target sequencesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.