The influence of excision repair on the distribution of N-propyl-N'-nitro-N-nitrosoguanidine-induced mutation in Escherichia coli.

doi:10.1093/mutage/5.2.127

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Article

The influence of excision repair on the distribution of N-propyl-N'-nitro-N-nitrosoguanidine-induced mutation in Escherichia coli.

Mutagenesis - 1 Mar 1990

van der Vliet G M, Zielenska M, Anderson M W, Glickman B W

Abstract excerpt

To determine the influence of excision repair on the distribution of N-propyl-N'-nitro-N-nitrosoguanidine (PNNG)-induced mutation, we have analysed the DNA sequence changes of mutation induced at the lacI gene of Escherichia coli in a UvrB- strain. The mutagenic specificity was similar to that fo...

Topics

Alkylating Agents
Base Sequence
DNA Repair
DNA, Bacterial
Escherichia coli
Methylnitronitrosoguanidine
Molecular Sequence Data
Mutagens
Mutation

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