Article
Polymorphisms of alcohol metabolizing enzymes in indigenous Mexican population: unusual high frequency of CYP2E1*c2 allele.
Alcoholism, clinical and experimental research - 1 Jan 2010
Gordillo-Bastidas Elizabeth, Panduro Arturo, Gordillo-Bastidas Daniela, Zepeda-Carrillo Eloy A, García-Bañuelos Jesús J, Muñoz-Valle José F, Bastidas-Ramírez Blanca E
Abstract excerpt
BACKGROUND: Alcohol abuse represents the major identified etiological factor of cirrhosis in México. ADH1B, ALDH2, and CYP2E1 have been considered candidate genes in alcohol-related diseases. Controversial results probably due to ethnic differences, among other factors, have been reported. Mexican Mestizos (MES) derive from the combination of indigenous, Spaniard, and African genes. Huichols (HUI) constitute an...
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