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Article

ADH and ALDH polymorphisms and alcohol dependence in Mexican and Native Americans.

The American journal of drug and alcohol abuse - 1 Sept 2012

Ehlers Cindy L, Liang Tiebing, Gizer Ian R

Abstract excerpt

BACKGROUND: Ethanol is primarily metabolized in the liver by two rate-limiting reactions: conversion of ethanol to acetaldehyde by alcohol dehydrogenase (ADH) and subsequent conversion of acetaldehyde to acetate by aldehyde dehydrogenase (ALDH). ADH and ALDH exist in multiple isozymes that differ in their kinetic properties. Notably, polymorphisms within the genes that encode for these isozymes vary in their...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22931071
DOI: 10.3109/00952990.2012.694526
PMCID: PMC3498484

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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