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Article

A haplotype analysis of CYP2E1 polymorphisms in relation to alcoholic phenotypes in Mexican Americans.

Alcoholism, clinical and experimental research - 1 Dec 2007

Yang Min, Tsuang John, Wan Yu-Jui Yvonne

Abstract excerpt

BACKGROUND: Studies regarding the association between the 4 polymorphisms of CYP2E1 (CYP2E1*1D, *5B, *6, and *1B) and alcoholism are inconsistent and inconclusive. The purpose of the present study was to clarify previously discordant studies by haplotype analysis in the Mexican American population. METHODS: The 4 polymorphisms of CYP2E1 were studied in 334 alcoholics and 365 controls. Genotype, allele, and...

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Identifiers

PMID: 18034693
DOI: 10.1111/j.1530-0277.2007.00533.x

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