Article
The ADH3*2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men.
Experimental and molecular pathology - 1 Apr 2003
Konishi Tamiko, Calvillo Maria, Leng Ai-She, Feng Jack, Lee Tony, Lee Hansen, Smith James Lafayette, Sial Shahid H, Berman Nancy, French Samuel, Eysselein Viktor, Lin Keh-Ming, Wan Yu-Jui Yvonne
Abstract excerpt
To identify the association between the polymorphisms of genes encoding alcohol metabolizing enzymes and alcoholism, the alcohol dehydrogenase 2 (ADH2), alcohol dehydrogenase 3 (ADH3), aldehyde dehydrogenase 2 (ALDH2), and cytochrome P450 2E1 (CYP2E1) genes were studied in 101 male Mexican American alcoholics. One hundred and four Mexican American nonalcoholic males served as controls. The allele frequency of...
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