Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans.

doi:10.1089/gte.1998.2.79

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Article

Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans.

Genetic testing - 1 Jan 1998

Wan Y J, Poland R E, Lin K M

Abstract excerpt

The major enzymes involved in the metabolism of ethanol are alcohol dehydrogenases (ADH) and aldehyde dehydrogenase (ALDH). Some of the isozymes of ADH are expressed polymorphically. Studies investigating a causal link between ADH expression and alcoholic liver disease (ALD) have so far produced conflicting results. The cytochrome P450 2E1 (CYP2E1) represents a second enzyme that can metabolize ethanol. Although...

Topics

Alcohol Dehydrogenase
Alcoholism
Aldehyde Dehydrogenase
Alleles
Asian People
Cytochrome P-450 CYP2E1
Enzyme Induction
Ethanol
Genetic Predisposition to Disease
Genotype
Humans
Isoenzymes
Mexican Americans
Polymorphism, Restriction Fragment Length
White People

Source

Open in PubMed

Identifiers

PMID: 10464602
DOI: 10.1089/gte.1998.2.79

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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