Article
Association between XRCC1 polymorphisms and head and neck cancer in a Hungarian population.
Anticancer research - 1 Oct 2009
Csejtei Andras, Tibold Antal, Koltai Katalin, Varga Zsuzsa, Szanyi Istvan, Gobel Gyula, Prantner Ida, Steffler Denes, Feher Gergely, De Blasio Antonio, Ember Istvan, Kiss Istvan
Abstract excerpt
BACKGROUND: Head and neck cancer is a significant current health problem in Hungary because the mortality of this cancer has increased by 387% in the last thirty-two years. Because of the important role of the XRCC1 gene in DNA repair, we wanted to test the effects of the Arg194Trp and Arg399Gln polymorphisms of XRCC1 on the clinical outcome of head and neck cancer. PATIENTS AND METHODS: A polymerase chain...
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