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Article

Association of RAD 51 135 G/C, 172 G/T and XRCC3 Thr241Met gene polymorphisms with increased risk of head and neck cancer.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Kayani Mahmood Akhtar, Khan Sumeera, Baig Ruqia Mehmood, Mahjabeen Ishrat

Abstract excerpt

Homologous recombination repair (HRR) plays an important role in protection against carcinogenic factors. Genes regulating the HRR mechanisms may impair their functions and consequently result in increased cancer susceptibility. RAD 51 and XRCC3 are key regulators of the HRR pathway and genetic variability in these may contribute to the appearance and progression of various cancers including head and neck cancer...

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Source

Identifiers

PMID: 25556492
DOI: 10.7314/apjcp.2014.15.23.10457

Genes

XRCC3
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of RAD 51 135 G/C, 172 G/T and XRCC3 Thr241Met gene polymorphisms with increased risk of head and neck cancer.PMID 25556492Read ↗

Polymorphisms of the XRCC3 C722T and the RAD51 G135C genes and the risk of head and neck cancer in a Polish population.Semantic proximity Read ↗

172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant.Semantic proximity Read ↗

RAD51 Gene 135G/C polymorphism and the risk of four types of common cancers: a meta-analysis.Semantic proximity Read ↗

Genetic variability of Xrcc3 and Rad51 modulates the risk of head and neck cancer.Semantic proximity Read ↗

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DNA repair gene XRCC1 polymorphisms and head and neck cancer risk: an updated meta-analysis including 16344 subjects.Semantic proximity Read ↗

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