Article
Allelic variants of XRCC1 and XRCC3 repair genes and susceptibility of oral cancer in Brazilian patients.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Feb 2013
Dos Reis Mariana Bisarro, Losi-Guembarovski Roberta, de Souza Fonseca Ribeiro Enilze Maria, Cavalli Iglenir João, Morita Maria Celeste, Ramos Gyl Henrique Albrecht, de Oliveira Benedito Valdecir, Mizuno Lauro Toyoshi, Rogatto Silvia Regina, de Syllos Cólus Ilce Mara
Abstract excerpt
BACKGROUND: The capacity for DNA repair is essential in maintaining cellular functions and homeostasis; however, this capacity can be altered based on DNA sequence variations in DNA repair genes, which may contribute to the onset of cancer. Many single-nucleotide polymorphisms (SNPs) in repair genes have been found to be associated with oral cancer. The aim of this study was to investigate the relationship...
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