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Article

Genetic variations in XRCC1 gene in sporadic head and neck cancer (HNC) patients.

Pathology oncology research : POR - 1 Apr 2013

Mahjabeen Ishrat, Baig Ruqia Mehmood, Masood Nosheen, Sabir Maimoona, Inayat Uzma, Malik Faraz Arshad, Kayani Mahmood Akhtar

Abstract excerpt

DNA repair gene polymorphisms have been implicated as susceptibility factors in cancer development. It is possible that DNA repair polymorphisms may also influence the risk of gene mutation. Polymorphisms in the DNA repair gene XRCC1 have been indicated to have a contributive role in DNA adduct formation and an increased risk of cancer development. 300 head and neck cancer patients and 150 controls were included...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23055018
DOI: 10.1007/s12253-012-9567-z

Genes

XRCC1

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