Article
XRCC1 and XRCC3 DNA repair gene polymorphisms in breast cancer women from the Lodz region of Poland.
Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Jan 2009
Sobczuk Anna, Romanowicz-Makowska Hanna, Fiks Tomasz, Baszczyński Jakub, Smolarz Beata
Abstract excerpt
AIM: Genetic polymorphism in XRCC1 and XRCC3 genes may influence DNA repair capacity and, in turn, confer predisposition to breast cancer. MATERIAL AND METHODS: In the present work the distribution of genotypes and frequency of alleles of the Arg194Trp and Arg399Gln polymorphism of XRCC1 and Trp241 Met polymorphism in XRCC3 in breast cancer women were analysed. Blood samples were obtained from 150 women with...
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