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Article

Prognostic significance of head and neck squamous cell carcinoma repair gene polymorphism.

Genetics and molecular research : GMR - 16 Oct 2015

Stur E, Agostini L P, Garcia F M, Peterle G T, Maia L L, Mendes S O, Anders Q S, Reis R S, Santos J A, Ventorim D P, Carvalho M B, Tajara E H, Santos M, Paula F, Silva-Conforti A M A, Louro I D

Abstract excerpt

The aims of this study were to analyze the polymorphisms XRCC1 Arg194Trp, XRCC1 Arg399Gln, XRCC3 Thr241Met, XPC Lys939Gln, ERCC1 Asn118Asn, and RAD51 -98G>C and to verify their influence on radiotherapy response and prognosis of patients with head and neck squamous cell carcinoma (HNSCC). Peripheral blood DNA was extracted from 311 patients and analyzed by PCR-RFLP. Our results showed that in irradiated oral and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Recurrence, Local

Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 26505394
DOI: 10.4238/2015.October.16.11

Genes

XRCC1
RAD51
XRCC3
ERCC1
XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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