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Article

Evaluation of XRCC1 Gene Polymorphism as a Biomarker in Head and Neck Cancer Patients Undergoing Chemoradiation Therapy.

International journal of radiation oncology, biology, physics - 1 Jul 2018

Nanda Sambit Swarup, Gandhi Ajeet Kumar, Rastogi Madhup, Khurana Rohini, Hadi Rahat, Sahni Kamal, Mishra Surendra Prasad, Srivastava Anoop K, Bhatt Madan Lal Brahma, Parmar Devendra

Abstract excerpt

PURPOSE: We evaluated the correlation of the x-ray repair cross complementing gene 1 (XRCC1) Arg194Trp polymorphism with clinical outcomes in head and neck squamous cell carcinoma (HNSCC) patients treated with concurrent chemoradiation therapy (CCRT). METHODS AND MATERIALS: In this prospective cohort study, we included 101 patients with HNSCC (oral cavity, pharynx, and larynx) who were aged ≥ 18 years, had stage...

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Source

Identifiers

PMID: 29893275
DOI: 10.1016/j.ijrobp.2018.03.039

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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