Article
Polymorphisms of the XRCC3 C722T and the RAD51 G135C genes and the risk of head and neck cancer in a Polish population.
Experimental and molecular pathology - 1 Dec 2010
Sliwinski Tomasz, Walczak Anna, Przybylowska Karolina, Rusin Pawel, Pietruszewska Wioletta, Zielinska-Blizniewska Hanna, Olszewski Jurek, Morawiec-Sztandera Alina, Jendrzejczyk Slawomir, Mlynarski Wojciech, Majsterek Ireneusz
Abstract excerpt
Genetic variations in DNA repair genes may affect an individual's susceptibility to head and neck cancer. We performed a case-control study to test the association between head and neck cancer risk and two polymorphisms: the C722T of the XRCC3 and the G135C of the RAD51-genes of DNA double strand break (DSB) repair by homologous recombination (HRR). Genotypes were determined by PCR-restriction fragment length...
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