Article
Successful implementation of a national HLA-B*5701 genetic testing service in Canada.
Tissue antigens - 1 Jan 2010
Lalonde R G, Thomas R, Rachlis A, Gill M J, Roger M, Angel J B, Smith G, Higgins N, Trottier B
Abstract excerpt
Abacavir is a nucleoside reverse transcriptase inhibitor (NRTI) that is used in combination antiretroviral therapy in HIV-infected patients. It is currently recommended as a preferred or an alternative NRTI in antiretroviral-naïve patients. The major toxicity of abacavir is a hypersensitivity reaction (HSR), which occurs in approximately 5% of treated patients. There is a strong association between the human...
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