Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association studies to detect adverse drug reactions: abacavir hypersensitivity as an example.

Pharmacogenomics - 1 Feb 2009

Hughes Arlene R, Brothers Cynthia H, Mosteller Michael, Spreen William R, Burns Daniel K

Abstract excerpt

Abacavir hypersensitivity (ABC HSR) is a treatment-limiting adverse event associated with the use of the antiretroviral medicine, abacavir. The objective of the ABC HSR pharmacogenetics program was to identify clinically useful genetic risk factors to predict an individual patient's risk for ABC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dideoxynucleosides
Share to Drug Hypersensitivity
Share to Drug-Induced Adverse Reactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-B Antigens

Share to Monoclonal and Polyclonal Antibodies Research

Share to Phenotype

Share to Research Design

Share to Reverse Transcriptase Inhibitors

Source

Identifiers

PMID: 19207023
DOI: 10.2217/14622416.10.2.225

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19207023-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association studies to detect adverse drug reactions: abacavir hypersensitivity as an example.PMID 19207023Read ↗

Abacavir Pharmacogenetics – From Initial Reports to Standard of CareSemantic proximity Read ↗

Successful translation of pharmacogenetics into the clinic: the abacavir example.Semantic proximity Read ↗

HLA-B*5701 screening for hypersensitivity to abacavir.Semantic proximity Read ↗

HLA-B*5701 screening for susceptibility to abacavir hypersensitivity.Semantic proximity Read ↗

First large, multicenter, open-label study utilizing HLA-B*5701 screening for abacavir hypersensitivity in North America.Semantic proximity Read ↗

HLA-B*5701 testing to predict abacavir hypersensitivitySemantic proximity Read ↗

Current trends in screening across ethnicities for hypersensitivity to abacavir.Semantic proximity Read ↗

Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations.Semantic proximity Read ↗

Clinical pharmacogenetics implementation consortium guidelines for HLA-B genotype and abacavir dosing.Semantic proximity Read ↗

PREDICT‐1 (CNA106030): the first powered, prospective trial of pharmacogenetic screening to reduce drug adverse eventsSemantic proximity Read ↗

[HLA-B*5701 and hypersensitivity reactions to abacavir. Study methods and clinical relevance].Semantic proximity Read ↗

Association of HLA-B*5701 genotypes and abacavir-induced hypersensitivity reaction: a systematic review and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.