Article
A sensitive and rapid alternative to HLA typing as a genetic screening test for abacavir hypersensitivity syndrome.
Pharmacogenetics and genomics - 1 May 2006
Martin Annalise M, Krueger Romano, Almeida Coral Ann, Nolan David, Phillips Elizabeth, Mallal Simon
Abstract excerpt
BACKGROUND: Abacavir hypersensitivity reaction (ABC HSR) is a potentially life-threatening adverse reaction that affects approximately 8% of patients that initiate this antiretroviral drug. Independent groups have shown a strong predictive association between ABC HSR and HLA-B*5701, indicating th...
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