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Article

Abacavir Pharmacogenetics – From Initial Reports to Standard of Care

3 May 2013

Abstract excerpt

Abacavir is a nucleoside analogue reverse transcriptase inhibitor indicated for the treatment of human immunodeficiency virus infection as part of a multidrug, highly active antiretroviral therapy regimen. Despite its efficacy, approximately 5% of individuals who receive abacavir develop an immune-mediated hypersensitivity reaction (HSR) that warrants immediate discontinuation of abacavir and switching to an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23649914
DOI: 10.1002/phar.1278

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