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Article

HLA-B*5701 testing to predict abacavir hypersensitivity

7 Dec 2010

Abstract excerpt

Abacavir is a nucleoside reverse transcriptase inhibitor used for combination antiretroviral therapy for treating human immunodeficiency virus (HIV) infection. An adverse effect from abacavir is a treatment-limiting hypersensitivity reaction, which can be severe and potentially life-threatening. Abacavir-induced hypersensitivity reaction has been associated with the presence of the major histocompatibility...

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PMID: 21151380
DOI: 10.1371/currents.rrn1203

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