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Article

HIF-dependent induction of adenosine receptor A2b skews human dendritic cells to a Th2-stimulating phenotype under hypoxia.

Immunology and cell biology - 1 Feb 2010

Yang Meixiang, Ma Chunhong, Liu Shuxun, Shao Qianqian, Gao Wenjuan, Song Bingfeng, Sun Jintang, Xie Qi, Zhang Yun, Feng Alei, Liu Yanguo, Hu Weixu, Qu Xun

Abstract excerpt

Hypoxia is a common characteristic of many pathological and physiological conditions that can markedly change cellular metabolism and cause the accumulation of extracellular adenosine. Recent studies have shown that adenosine can modulate the function of certain immune cell types through binding with different adenosine receptors. Our previous studies have shown that hypoxia has an effect on the biological...

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PMID: 19841638
DOI: 10.1038/icb.2009.77

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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