Article

ConSeqUMI, an error-free nanopore sequencing pipeline to identify and extract individual nucleic acid molecules from heterogeneous samples

2025-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Nanopore sequencing has revolutionized genetic analysis by offering linkage information across megabase-scale genomes. However, the high intrinsic error rate of nanopore sequencing impedes the analysis of complex heterogeneous samples, such as viruses, bacteria, complex libraries, and edited cell lines. Achieving high accuracy in single-molecule sequence identification would significantly advanc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5f6c4467-7de0-55fd-a718-48fbec3745e6
DOI: 10.1101/2025.04.03.647077

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ConSeqUMI, an error-free nanopore sequencing pipeline to identify and extract individual nucleic acid molecules from heterogeneous samplesDOI 10.1101/2025.04.03.647077Read

SquiDBase: a community resource of raw nanopore data from microbesSemantic proximity Read

<i>In silico</i> analyses identifies sequence contamination thresholds for Nanopore-generated SARS-CoV2 sequencesSemantic proximity Read

Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysisSemantic proximity Read

Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysisSemantic proximity Read

CAS12A-TARGETED MULTIPLEXED NANOPORE SEQUENCINGSemantic proximity Read

Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysisSemantic proximity Read

A whole-genome sequencing dataset of nanopore raw signals for bacterial genotyping and methylation analysis.Semantic proximity Read

Real-time Nanopore de novo assembly of ESKAPE pathogens: Implications for antibiotic stewardshipSemantic proximity Read

High-Fidelity Nanopore Sequencing of Ultra-Short DNA SequencesSemantic proximity Read

NanoSimFormer: An end-to-end Transformer-based simulator for nanopore sequencing signal dataSemantic proximity Read

A multicenter study on accuracy and reproducibility of nanopore sequencing-based genotyping of bacterial pathogens.Semantic proximity Read

Evaluation of Oxford Nanopore Technologies workflows for genomic epidemiology of outbreak‐associated bacterial isolates in the clinical settingSemantic proximity Read