Article
Single-molecule DNA sequencing of a viral genome.
Science (New York, N.Y.) - 4 Apr 2008
Harris Timothy D, Buzby Phillip R, Babcock Hazen, Beer Eric, Bowers Jayson, Braslavsky Ido, Causey Marie, Colonell Jennifer, Dimeo James, Efcavitch J William, Giladi Eldar, Gill Jaime, Healy John, Jarosz Mirna, Lapen Dan, Moulton Keith, Quake Stephen R, Steinmann Kathleen, Thayer Edward, Tyurina Anastasia, Ward Rebecca, Weiss Howard, Xie Zheng
Abstract excerpt
The full promise of human genomics will be realized only when the genomes of thousands of individuals can be sequenced for comparative analysis. A reference sequence enables the use of short read length. We report an amplification-free method for determining the nucleotide sequence of more than 2...
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