Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The range of human APOBEC3H sensitivity to lentiviral Vif proteins.

Journal of virology - 1 Jan 2010

Li Melody M H, Wu Lily I, Emerman Michael

Abstract excerpt

The APOBEC3H gene is polymorphic in humans, with four major population-dependent haplotypes that encode proteins with different levels of antiviral activity. Haplotype II, present most frequently in African populations, encodes the most stable protein and is most active against human immunodeficiency virus type 1 (HIV-1). In contrast to human APOBEC3G, which can be completely counteracted by HIV-1 Vif, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aminohydrolases
Share to APOBEC-3G Deaminase
Share to Cytidine Deaminase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytosine Deaminase

Share to Gene Products, vif

Share to Human Immunodeficiency Virus Proteins

Share to Leukocytes, Mononuclear

Source

Open in PubMed Open full text

Identifiers

PMID: 19828612
DOI: 10.1128/JVI.01344-09
PMCID: PMC2798431

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The range of human APOBEC3H sensitivity to lentiviral Vif proteins.PMID 19828612Read ↗

Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity.Semantic proximity Read ↗

A single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity.Semantic proximity Read ↗

The Activity Spectrum of Vif from Multiple HIV-1 Subtypes against APOBEC3G, APOBEC3F, and APOBEC3HSemantic proximity Read ↗

Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1Semantic proximity Read ↗

Analysis of Human APOBEC3H Haplotypes and Anti-Human Immunodeficiency Virus Type 1 ActivitySemantic proximity Read ↗

Human Cytidine Deaminase APOBEC3H Restricts HIV-1 ReplicationSemantic proximity Read ↗

Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H.Semantic proximity Read ↗

A positively selected APOBEC3H haplotype is associated with natural resistance to HIV-1 infection.Semantic proximity Read ↗

The Structural Interface between HIV-1 Vif and Human APOBEC3HSemantic proximity Read ↗

Recurrent Loss of APOBEC3H Activity during Primate EvolutionSemantic proximity Read ↗

A single amino acid in human APOBEC3F alters susceptibility to HIV-1 Vif.Semantic proximity Read ↗

Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 proteaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.