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Article

A single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity.

Journal of virology - 1 Feb 2010

Zhen Anjie, Wang Tao, Zhao Ke, Xiong Yong, Yu Xiao-Fang

Abstract excerpt

Several variants of APOBEC3H (A3H) have been identified in different human populations. Certain variants of this protein are particularly potent inhibitors of retrotransposons and retroviruses, including HIV-1. However, it is not clear whether HIV-1 Vif can recognize and suppress the antiviral activity of A3H variants, as it does with other APOBEC3 proteins. We now report that A3H_Haplotype II (HapII), a potent...

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Source

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Identifiers

PMID: 19939923
DOI: 10.1128/JVI.01509-09
PMCID: PMC2812409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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