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Article

Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H.

Journal of virology - 1 Jan 2009

Harari Ariana, Ooms Marcel, Mulder Lubbertus C F, Simon Viviana

Abstract excerpt

Human APOBEC3H belongs to the APOBEC3 family of cytidine deaminases that potently inhibit exogenous and endogenous retroviruses. The impact of single nucleotide polymorphisms (SNP) and alternative splicing on the antiretroviral activity of human APOBEC3H is currently unknown. In this study, we show that APOBEC3H transcripts derived from human peripheral blood mononuclear cells are polymorphic in sequence and...

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Identifiers

PMID: 18945781
DOI: 10.1128/JVI.01665-08
PMCID: PMC2612324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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