Article
Mannose-binding lectin concentrations, MBL2 polymorphisms, and susceptibility to respiratory tract infections in young men.
The Journal of infectious diseases - 15 Oct 2008
Rantala Aino, Lajunen Taina, Juvonen Raija, Bloigu Aini, Silvennoinen-Kassinen Sylvi, Peitso Ari, Saikku Pekka, Vainio Olli, Leinonen Maija
Abstract excerpt
BACKGROUND: Mannose-binding lectin (MBL) is an important component of innate immunity, and its deficiency is associated with susceptibility to recurrent infections. METHODS: This exploratory study investigated the association of serum MBL concentrations and MBL2 gene polymorphisms with respiratory tract infections in young men. We genotyped 6 single-nucleotide polymorphisms (SNPs) in the promoter region (alleles...
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