Article
3'UTR mediated regulation of the cyclin D1 proto-oncogene.
Cell cycle (Georgetown, Tex.) - 1 Nov 2009
Deshpande Anagha, Pastore Alessandro, Deshpande Aniruddha J, Zimmermann Yvonne, Hutter Grit, Weinkauf Marc, Buske Christian, Hiddemann Wolfgang, Dreyling Martin
Abstract excerpt
In mantle cell lymphoma (MCL), overexpression of cyclin D1 is the hallmark of malignant transformation and results from it's juxtaposition to the immunoglobulin heavy chain enhancer. In addition, genomic deletions or point mutations leading to premature truncation of the cyclin D1 3' untranslated...
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