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Article

The mitA gene of Aspergillus fumigatus is required for mannosylation of inositol-phosphorylceramide, but is dispensable for pathogenicity.

Fungal genetics and biology : FG & B - 1 Feb 2010

Kotz Andrea, Wagener Johannes, Engel Jakob, Routier Françoise, Echtenacher Bernd, Pich Andreas, Rohde Manfred, Hoffmann Petra, Heesemann Jürgen, Ebel Frank

Abstract excerpt

GDP-mannose:inositol-phosphorylceramide (MIPC)-derived glycosphingolipids are important pathogen-associated molecular patterns (PAMP) of Candida albicans and according to recently published data also of Aspergillus fumigatus. MIPC transferases are essential for the synthesis of MIPC, but have so far been studied only in Saccharomyces cerevisiae and C. albicans. Here, we have identified MitA as the only MIPC...

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PMID: 19822220
DOI: 10.1016/j.fgb.2009.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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