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<i>Candida albicans</i> cells lacking AP-2 have defective hyphae and are avirulent despite increased host uptake and intracellular proliferation in macrophages

2023-08-03

Abstract excerpt

Candida albicans is a commensal microbe and opportunistic human pathogen. The yeast can be recognised and taken up by macrophages via interactions with its cell wall, a complex polysaccharide structure containing several components that are specifically recognised by immune cell receptors. Following uptake Candida can respond in the host environment by switching from a yeast to hyphal morphology which facilitates...

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Literature Corpus work
6f00e895-19ca-5004-afc2-0b46678dbb02
DOI
10.1101/2023.08.03.551781
Open publication

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