Article
Role of protein phosphomannosylation in the Candida tropicalis-macrophage interaction.
FEMS yeast research - 1 Aug 2018
Hernández-Chávez Marco J, Franco Bernardo, Clavijo-Giraldo Diana M, Hernández Nahúm V, Estrada-Mata Eine, Mora-Montes Héctor Manuel
Abstract excerpt
Candida tropicalis is an opportunistic fungal pathogen responsible for mucosal and systemic infections. The cell wall is the initial contact point between a fungal cell and the host immune system, and mannoproteins are important components that play key roles when interacting with host cells. In Candida albicans, mannans are modified by mannosyl-phosphate moieties, named phosphomannans, which can work as...
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