Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Candida albicans Pmr1p, a secretory pathway P-type Ca2+/Mn2+-ATPase, is required for glycosylation and virulence.

The Journal of biological chemistry - 17 Jun 2005

Bates Steven, MacCallum Donna M, Bertram Gwyneth, Munro Carol A, Hughes H Bleddyn, Buurman Ed T, Brown Alistair J P, Odds Frank C, Gow Neil A R

Abstract excerpt

The cell surface of Candida albicans is the immediate point of contact with the host. The outer layer of the cell wall is enriched in highly glycosylated mannoproteins that are implicated in many aspects of the host-fungus interaction. Glycosylation of cell wall proteins is initiated in the endoplasmic reticulum and then elaborated in the Golgi as the protein passes through the secretory pathway. Golgi-bound...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acid Phosphatase
Share to Benzenesulfonates

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromatography, Ion Exchange

Share to Chromatography, Thin Layer

Share to Congo Red

Share to Egtazic Acid

Share to Hygromycin B

Share to Mannans

Source

Identifiers

PMID: 15843378
DOI: 10.1074/jbc.M502162200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Candida albicans Pmr1p, a secretory pathway P-type Ca2+/Mn2+-ATPase, is required for glycosylation and virulence.PMID 15843378Read ↗

The medial-Golgi ion pump Pmr1 supplies the yeast secretory pathway with Ca2+ and Mn2+ required for glycosylation, sorting, and endoplasmic reticulum-associated protein degradation.Semantic proximity Read ↗

bcpmr1 encodes a P-type Ca(2+)/Mn(2+)-ATPase mediating cell-wall integrity and virulence in the phytopathogen Botrytis cinerea.Semantic proximity Read ↗

The Golgi GDPase of the fungal pathogen Candida albicans affects morphogenesis, glycosylation, and cell wall properties.Semantic proximity Read ↗

Outer chain N-glycans are required for cell wall integrity and virulence of Candida albicans.Semantic proximity Read ↗

Molecular and phenotypic analysis of CaVRG4, encoding an essential Golgi apparatus GDP-mannose transporter.Semantic proximity Read ↗

Role of Protein Glycosylation in Candida parapsilosis Cell Wall Integrity and Host InteractionSemantic proximity Read ↗

The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution.Semantic proximity Read ↗

A phenomics approach in yeast links proton and calcium pump function in the Golgi.Semantic proximity Read ↗

Pmr-1 gene affects susceptibility of Caenorhabditis elegans to Staphylococcus aureus infection through glycosylation and stress response pathways' alterations.Semantic proximity Read ↗

Multiple functions of Pmt1p-mediated protein O-mannosylation in the fungal pathogen Candida albicans.Semantic proximity Read ↗

A multifunctional mannosyltransferase family in Candida albicans determines cell wall mannan structure and host-fungus interactions.Semantic proximity Read ↗

The MP65 gene is required for cell wall integrity, adherence to epithelial cells and biofilm formation in Candida albicansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.