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Article

Engineering of a Mouse for the in Vivo Profiling of Estrogen Receptor Activity

1 Jul 2001

Abstract excerpt

In addition to their well known control of reproductive functions, estrogens modulate important physiological processes. The identification of compounds with tissue-selective activity will lead to new drugs mimicking the beneficial effects of estrogen on the prevention of osteoporosis and cardiovascular or neurodegenerative diseases, while avoiding its detrimental proliferative effects. As an innovative model for...

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Share to Cytokine Signaling Pathways and Interactions
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Identifiers

PMID: 11435611
DOI: 10.1210/mend.15.7.0658

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