Article
Mms1-Mms22 complex protects genome integrity in Schizosaccharomyces pombe.
DNA repair - 3 Dec 2009
Dovey Claire L, Aslanian Aaron, Sofueva Sevil, Yates John R, Russell Paul
Abstract excerpt
Mms1 and Mms22 are subunits of an Rtt101-based E3 ubiquitin ligase required for replication of damaged DNA templates in Saccharomyces cerevisiae. The function and evolutionary conservation of this DNA repair module are unknown. Here we report the characterization of an Mms1 ortholog in Schizosaccharomyces pombe. Fission yeast Mms1 was discovered through its physical association with S. pombe Mms22 (also known as...
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