Article
Mismatch repair proteins and mitotic genome stability.
Mutation research - 30 Jun 2000
Harfe B D, Jinks-Robertson S
Abstract excerpt
Mismatch repair (MMR) proteins play a critical role in maintaining the mitotic stability of eukaryotic genomes. MMR proteins repair errors made during DNA replication and in their absence, mutations accumulate at elevated rates. In addition, MMR proteins inhibit recombination between non-identical DNA sequences, and hence prevent genome rearrangements resulting from interactions between repetitive elements. This...
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