Article
The Role of Mms22p in DNA Damage Response in Candida albicans.
G3 (Bethesda, Md.) - 4 Oct 2015
Yan Lan, Xiong Juan, Lu Hui, Lv Quan-zhen, Ma Qian-yao, Côte Pierre, Whiteway Malcolm, Jiang Yuan-ying
Abstract excerpt
To ensure correct DNA replication, eukaryotes have signaling pathways that respond to replication-associated DNA damage and trigger repair. In both Saccharomyces cerevisiae and Schizosaccharomyces pombe, a complex of proteins, including the cullin protein Rtt101p and two adapter proteins Mms22p and Mms1p, is important for proper response to replication stress. We have investigated this system in Candida albicans....
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