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Article

Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast.

PLoS genetics - 23 Sept 2010

Cavero Santiago, Limbo Oliver, Russell Paul

Abstract excerpt

Replication Protein A (RPA) is a heterotrimeric, single-stranded DNA (ssDNA)-binding complex required for DNA replication and repair, homologous recombination, DNA damage checkpoint signaling, and telomere maintenance. Whilst the larger RPA subunits, Rpa1 and Rpa2, have essential interactions with ssDNA, the molecular functions of the smallest subunit Rpa3 are unknown. Here, we investigate the Rpa3 ortholog Ssb3...

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Identifiers

PMID: 20885790
DOI: 10.1371/journal.pgen.1001138
PMCID: PMC2944793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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