Phenotypic changes in ciprofloxacin-resistant Staphylococcus aureus.

doi:10.1016/j.resmic.2009.09.013

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Article

Phenotypic changes in ciprofloxacin-resistant Staphylococcus aureus.

Research in microbiology - 1 Dec 2009

Mesak Lili R, Davies Julian

Abstract excerpt

The work described here continues our studies of the effects of subinhibitory concentrations of antibiotics on SOS and DNA repair gene expression in Staphylococcus aureus. Mitomycin C and the new-generation fluoroquinolone moxifloxacin induced expression of SOS response genes (lexA, recA, sosA, and umuC) in a ciprofloxacin-resistant Cip(r)I strain of S. aureus. To examine phenotypic changes in Cip(r) strains...

Topics

Antibiotics, Antineoplastic
Aza Compounds
Bacterial Proteins
Ciprofloxacin
DNA Mismatch Repair
Drug Resistance, Bacterial
Fluoroquinolones
Gene Expression
Gene Expression Regulation, Bacterial
Mitomycin
Moxifloxacin
Multidrug Resistance-Associated Proteins
Mutation
Oligonucleotide Array Sequence Analysis
Phenotype
Quinolines
SOS Response, Genetics
Staphylococcus aureus

Source

Open in PubMed

Identifiers

PMID: 19818400
DOI: 10.1016/j.resmic.2009.09.013

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