Article
An unusually proximal deletion on the short arm of chromosome 3 in a patient with small cell lung cancer.
Genomics - 1 Jan 1991
Daly M C, Douglas J B, Bleehen N M, Hastleton P, Twentyman P R, Sundaresan V, Carritt B, Bergh J, Rabbitts P H
Abstract excerpt
The tumors of patients with small cell lung carcinoma (SCLC) frequently exhibit the loss of alleles at polymorphic loci on the short arm of chromosome 3. We report the genotype analysis of six SCLC patients obtained using 15 chromosome 3 probes that identified 19 restriction fragment length polym...
Topics
- Alleles
- Carcinoma, Small Cell
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 3
- Densitometry
- Genotype
- Heterozygote
- Humans
- Lung Neoplasms
- Polymorphism, Restriction Fragment Length
- Tumor Cells, Cultured