Article
Staphylococcus aureus binds to the N-terminal region of corneodesmosin to adhere to the stratum corneum in atopic dermatitis
23 Dec 2020
Abstract excerpt
Significance Staphylococcus aureus colonizes skin of patients with atopic dermatitis (AD), increasing disease severity. Colonization involves bacterial adhesion to skin corneocytes, and elucidating the molecular basis of interactions governing adhesion is crucial to further our understanding of pathogenesis and inform targeted therapies. We identify host and pathogen factors that enable adhesion. We demonstrate...
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