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Article

Functional genetic variants in DC-SIGNR are associated with mother-to-child transmission of HIV-1.

PloS one - 7 Oct 2009

Boily-Larouche Geneviève, Iscache Anne-Laure, Zijenah Lynn S, Humphrey Jean H, Mouland Andrew J, Ward Brian J, Roger Michel

Abstract excerpt

BACKGROUND: Mother-to-child transmission (MTCT) is the main cause of HIV-1 infection in children worldwide. Given that the C-type lectin receptor, dendritic cell-specific ICAM-grabbing non-integrin-related (DC-SIGNR, also known as CD209L or liver/lymph node-specific ICAM-grabbing non-integrin (L-SIGN)), can interact with pathogens including HIV-1 and is expressed at the maternal-fetal interface, we hypothesized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19809496
DOI: 10.1371/journal.pone.0007211
PMCID: PMC2752805

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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