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Article

The polymorphisms in DC-SIGNR affect susceptibility to HIV type 1 infection.

AIDS research and human retroviruses - 1 May 2007

Wichukchinda Nuanjun, Kitamura Yoshihiro, Rojanawiwat Archawin, Nakayama Emi E, Song Haihan, Pathipvanich Panita, Auwanit Wattana, Sawanpanyalert Pathom, Iwamoto Aikichi, Shioda Tatsuo, Ariyoshi Koya

Abstract excerpt

Dendritic cell-specific intercellular adhesion molecule-3 (ICAM-3) grabbing nonintegrin (DC-SIGN) and its homologue DC-SIGNR (DC-SIGN related) have been thought to play an important role in establishing HIV infection by enhancing trans-infection of CD4(+)T cells in the regional lymph nodes. To identify polymorphisms associated with HIV-exposed seronegative (ESN) individuals in Thais, genomic DNA from 102...

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Identifiers

PMID: 17530994
DOI: 10.1089/aid.2006.0212

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The polymorphisms in DC-SIGNR affect susceptibility to HIV type 1 infection.PMID 17530994Read ↗

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