Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KIR-HLA and maternal-infant HIV-1 transmission in sub-Saharan Africa.

PloS one - 8 Feb 2011

Paximadis Maria, Minevich Gregory, Winchester Robert, Schramm Diana B, Gray Glenda E, Sherman Gayle G, Coovadia Ashraf H, Kuhn Louise, Tiemessen Caroline T

Abstract excerpt

Numerous studies have suggested a role for natural killer (NK) cells in attenuation of HIV-1 disease progression via recognition by killer-cell immunoglobulin-like receptors (KIRs) of specific HLA class I molecules. The role of KIR and HLA class I has not been addressed in the context of maternal-infant HIV-1 transmission. KIR and HLA class I B and C genes from 224 HIV-1-infected mothers and 222 infants (72...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Killer Cells, Natural
Share to Africa South of the Sahara

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HIV Infections

Share to HLA Antigens

Share to Infectious Disease Transmission, Vertical

Share to Ligands

Share to Receptors, KIR

Source

Open in PubMed Open full text

Identifiers

PMID: 21346814
DOI: 10.1371/journal.pone.0016541
PMCID: PMC3035631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KIR-HLA and maternal-infant HIV-1 transmission in sub-Saharan Africa.PMID 21346814Read ↗

Killer-Cell Immunoglobulin-Like Receptors (KIR) in HIV-Exposed Infants in Cameroon.Semantic proximity Read ↗

KIR2DS4 allelic variants: Differential effects on in utero and intrapartum HIV-1 mother-to-child transmission.Semantic proximity Read ↗

Association of maternal KIR gene content polymorphisms with reduction in perinatal transmission of HIV-1.Semantic proximity Read ↗

Diversity in KIR gene repertoire in HIV-1 exposed infected and uninfected infants: A study from India.Semantic proximity Read ↗

Impact of HLA Allele-KIR Pairs on HIV Clinical Outcome in South Africa.Semantic proximity Read ↗

Differential association of gene content polymorphisms of killer cell immunoglobulin-like receptors with placental malaria in HIV- and HIV+ mothers.Semantic proximity Read ↗

Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women.Semantic proximity Read ↗

Mother-to-child transmission of HIV-1: strong association with certain maternal HLA-B alleles independent of viral load implicates innate immune mechanisms.Semantic proximity Read ↗

Killer Cell Immunoglobulin-Like Receptor Alleles Alter HIV Disease in Children.Semantic proximity Read ↗

Natural killer cell-mediated innate sieve effect on HIV-1: the impact of KIR/HLA polymorphism on HIV-1 subtype-specific acquisition in east Africa.Semantic proximity Read ↗

Effects of the killer immunoglobulin-like receptor (KIR) polymorphisms on HIV acquisition: A meta-analysis.Semantic proximity Read ↗

Functional genetic variants in DC-SIGNR are associated with mother-to-child transmission of HIV-1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.