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Article

Transmissibility of atypical scrapie in ovine transgenic mice: major effects of host prion protein expression and donor prion genotype.

PloS one - 6 Oct 2009

Arsac Jean-Noël, Bétemps Dominique, Morignat Eric, Féraudet Cécile, Bencsik Anna, Aubert Denise, Grassi Jacques, Baron Thierry

Abstract excerpt

Atypical scrapie or Nor98 has been identified as a transmissible spongiform encephalopathy (TSE) that is clearly distinguishable from classical scrapie and BSE, notably regarding the biochemical features of the protease-resistant prion protein PrP(res) and the genetic factors involved in susceptibility to the disease. In this study we transmitted the disease from a series of 12 French atypical scrapie isolates in...

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Identifiers

PMID: 19806224
DOI: 10.1371/journal.pone.0007300
PMCID: PMC2752806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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