Article
Selection of distinct strain phenotypes in mice infected by ovine natural scrapie isolates similar to CH1641 experimental scrapie.
Journal of neuropathology and experimental neurology - 1 Feb 2012
Vulin Johann, Beck Katy E, Bencsik Anna, Lakhdar Latefa, Spiropoulos John, Baron Thierry
Abstract excerpt
A few cases of transmissible spongiform encephalopathies in sheep have been described in France in which the protease-resistant prion protein (PrP(res)) exhibited some features in Western blot of experimental bovine spongiform encephalopathy in sheep. Their molecular characteristics were indistinguishable from those produced in the CH1641 experimental scrapie isolate. Four of these CH1641-like isolates were...
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