Genetic and infectious prion diseases.

doi:10.1001/archneur.1993.00540110011002

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Article

Genetic and infectious prion diseases.

Archives of neurology - 1 Nov 1993

Prusiner S B

Abstract excerpt

Enriching fractions from Syrian hamster (SHa) brain for scrapie prion infectivity led to the discovery of the prion protein (PrP). Prion diseases include scrapie of sheep and bovine spongiform encephalopathy of cattle as well as Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker syndrome (GSS) of humans. Transgenic (Tg) mice expressing both SHa and mouse (Mo) PrP genes were used to probe the...

Topics

Animal Diseases
Animals
Cattle
Creutzfeldt-Jakob Syndrome
Encephalopathy, Bovine Spongiform
Gerstmann-Straussler-Scheinker Disease
Goat Diseases
Goats
Humans
Iatrogenic Disease
Kuru
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

PrPSc Proteins

Prion Diseases

Prions

Rats

Rodent Diseases

Source

Open in PubMed

Identifiers

PMID: 8105771
DOI: 10.1001/archneur.1993.00540110011002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8105771-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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